TB-500 (Thymosin β4 acetate)

Description

Product Specifications

Form: Lyophilized peptide powder

Strength: Add the product-specific strength

Peptide Length: 7 amino acid residues

Peptide Classification: Synthetic N-terminally acetylated thymosin beta-4-derived research peptide

Peptide Sequence: Ac-Leu-Lys-Lys-Thr-Glu-Thr-Gln-OH

One-Letter Sequence: Ac-LKKTETQ-OH

N-Terminal Modification: Acetylated

C-Terminal Modification: Free carboxyl terminus

Molecular Formula: C₃₈H₆₈N₁₀O₁₄ for the free-base form

Molecular Weight: Approximately 889.01 g/mol for the free-base form

CAS Number: 885340-08-9

Purity: ≥99%, where confirmed through batch-specific HPLC analysis

Appearance: White to off-white lyophilized peptide powder

Intended Use: Laboratory research and analytical applications only

FDA documentation distinguishes TB-500 free base from TB-500 acetate and reports the free-base specifications as CAS 885340-08-9, C₃₈H₆₈N₁₀O₁₄, and 889.01 g/mol.

Research Applications

Analytical characterization using HPLC, UPLC, and LC-MS workflows

Evaluation of thymosin beta-4-derived short peptide sequences

Investigation of peptide-mediated molecular interactions under controlled in vitro conditions

Structure-activity analysis of N-terminally acetylated peptide fragments

Comparative assessment of TB-500 and related thymosin beta-4-derived materials

Peptide identity, purity, molecular weight, and structural integrity analysis

Evaluation of chromatographic and mass-spectrometric peptide profiles

Concentration-dependent molecular interaction studies under defined assay conditions

Stability profiling under controlled temperature, pH, buffer, and storage conditions

Quality Documentation

A batch-specific Certificate of Analysis and applicable analytical documentation should be available for each lot. Verify peptide identity, exact sequence, N-terminal acetylation, purity, molecular weight, counterion status, formulation details, and batch information against the records supplied with the individual product.

The molecular formula and molecular weight listed above correspond to TB-500 free base. FDA documentation lists the 1:1 acetate form separately as C₃₈H₆₈N₁₀O₁₄·CH₃COOH with an approximate molecular weight of 949.1 g/mol and specifically notes that some supplier listings incorrectly use the free-base CAS number for TB-500 acetate.

Batch-specific HPLC and mass-spectrometric documentation should therefore be used as the final reference for product specifications.

For Laboratory Research Use Only

This product is intended exclusively for controlled laboratory and in vitro research. Not for human or veterinary use. Not for diagnostic, therapeutic, clinical, cosmetic, or household applications.